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Eye: peptides in published research

Sources checked 2026-10-07 · 5 compounds · 6 cited studies

Scope: Cornea, tear film, optic nerve and intraocular pressure. Each entry names the model and the tissue that a published study looked at, with the citation. It describes what was studied, not what was found, and a listing here is not a claim that a compound does anything in that organ.

ARA-290 (cibinetide)

  • Human Adults with sarcoidosis-associated small nerve fiber loss; corneal nerve fiber abundance. Published 2017 · PubMed PMID 28475703 ↗

Also listed under: Brain & nervous system, Heart & blood vessels, Kidney & urinary tract, Gut & digestive tract

BPC-157

  • Animal Rat glaucoma model (three episcleral veins cauterized); intraocular pressure. Published 2021 · PubMed PMID 35052769 ↗

Also listed under: Brain & nervous system, Heart & blood vessels, Liver, Kidney & urinary tract, Gut & digestive tract, Skin, Muscle & tendon

Klotho (α-Klotho)

  • Animal Klotho knockout mice; myelination of the optic nerve examined at the ultrastructural level. Published 2013 · PubMed PMID 23365232 ↗

Also listed under: Brain & nervous system, Heart & blood vessels, Kidney & urinary tract, Muscle & tendon, Bone & cartilage, Lungs & airways

SS-31 (elamipretide)

  • Human Phase II randomized trial of topical eye drops in 12 adults with Leber hereditary optic neuropathy. Published 2024 · PubMed PMID 37923251 ↗

Also listed under: Brain & nervous system, Heart & blood vessels, Muscle & tendon

TB-500 (thymosin beta-4)

  • Human Phase 2 trial of thymosin beta 4 eye drops in 9 adults with severe dry eye. Published 2015 · PubMed PMID 25826322 ↗
  • Human Phase II trial of thymosin beta 4 ophthalmic solution in 72 adults with moderate to severe dry eye (controlled adverse environment model). Published 2015 · PubMed PMID 26056426 ↗

Also listed under: Brain & nervous system, Heart & blood vessels, Liver, Skin, Bone & cartilage, Lungs & airways

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See also: all organ systems · all compound profiles.